A UK Retrospective Cohort Found That Patients With Higher Levels of Time-averaged Proteinuria Had More Rapid eGFR Loss1,*,†
Even proteinuria levels typically perceived as low risk (<0.88 g/g) may also indicate a risk of disease progression1
Click on image to enlarge.
†<0.88 g/g is approximately equivalent to <1 g/day.1
Image adapted from: Pitcher D, Braddon F, Hendry B, et al. Long-term outcomes in IgA nephropathy. Clin J Am Soc Nephrol. 2023;18(6):727-738. doi:10.2215/CJN.0000000000000135
A UK retrospective cohort found that 30% of patients with a time-averaged proteinuria range of 0.44 to <0.88 g/g† reached kidney failure within 10 years1,*
Click on image to enlarge.
†<0.88 g/g is approximately equivalent to <1 g/day.1
Image adapted from: Pitcher D, Braddon F, Hendry B, et al. Long-term outcomes in IgA nephropathy. Clin J Am Soc Nephrol. 2023;18(6):727-738. doi:10.2215/CJN.0000000000000135
In all age groups, the majority of patients developed kidney failure in 10 to 15 years1
eGFR, estimated glomerular filtration rate; IgAN, immunoglobulin A nephropathy; IQR, interquartile range; UPCR, urine protein-creatinine ratio.
Reference: 1. Pitcher D, Braddon F, Hendry B, et al. Long-term outcomes in IgA nephropathy. Clin J Am Soc Nephrol. 2023;18(6):727-738. doi:10.2215/CJN.0000000000000135