A UK Retrospective Cohort Found That Patients With Higher Levels of Time-averaged Proteinuria Had More Rapid eGFR Loss^1,*,†

Even proteinuria levels typically perceived as low risk (<0.88 g/g) may also indicate a risk of disease progression¹

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^†<0.88 g/g is approximately equivalent to <1 g/day.¹

Image adapted from: Pitcher D, Braddon F, Hendry B, et al. Long-term outcomes in IgA nephropathy. Clin J Am Soc Nephrol. 2023;18(6):727-738. doi:10.2215/CJN.0000000000000135

A UK retrospective cohort found that 30% of patients with a time-averaged proteinuria range of 0.44 to <0.88 g/g^† reached kidney failure within 10 years^1,*

Click on image to enlarge.

^†<0.88 g/g is approximately equivalent to <1 g/day.¹

Image adapted from: Pitcher D, Braddon F, Hendry B, et al. Long-term outcomes in IgA nephropathy. Clin J Am Soc Nephrol. 2023;18(6):727-738. doi:10.2215/CJN.0000000000000135

eGFR, estimated glomerular filtration rate; IgAN, immunoglobulin A nephropathy; IQR, interquartile range; UPCR, urine protein-creatinine ratio.

Reference: 1. Pitcher D, Braddon F, Hendry B, et al. Long-term outcomes in IgA nephropathy. Clin J Am Soc Nephrol. 2023;18(6):727-738. doi:10.2215/CJN.0000000000000135